研究者らは,GSDMDタンパク質を含む炎症の主要なメカニズムを特定し,それが,症や自己炎症性疾患の治療につながる可能性がある. Researchers identify key mechanisms of inflammation involving protein GSDMD, potentially leading to treatments for sepsis and autoinflammatory diseases.

細胞膜に毛穴を形成し 炎症反応と細胞死を促進する タンパク質ガズダーミンD (GSDMD) を含む炎症の 重要なメカニズムを 発見しました Researchers at the University Hospital Bonn and the University of Bonn have uncovered key mechanisms of inflammation involving the protein gasdermin D (GSDMD), which forms pores in cell membranes, facilitating inflammatory responses and cell death. ナノボディを使って これらの断片は 毛穴形成を抑制し セプシスや 自己炎症性疾患などの 治療に繋がる可能性があることがわかりました Utilizing nanobodies, they found these fragments can inhibit pore formation, potentially leading to treatments for conditions like sepsis and autoinflammatory diseases. 論文は"Nature Communications"に 詳しく載っています Their findings are detailed in "Nature Communications."